Pesquisa da associação do BNP com a insuficiência cardíaca
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2016-11
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Hoerlle, Jairo Luís
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A insuficiência cardíaca (IC) é uma síndrome complexa, a qual, apesar dos avanços da medicina relacionados ao diagnóstico e tratamento de doenças cardiovasculares, é responsável por uma alta taxa de mortalidade em todo o mundo. Fatores como estilo de vida, dificuldade de diagnóstico rápido e envelhecimento da população contribuem para o aumento da incidência e prevalência de tal patologia. Um grande aliado para o diagnóstico laboratorial precoce da IC, embora ainda pouco solicitado nas avaliações clínicas, é o peptídeo natriurético tipo B (BNP). OBJETIVOS: determinar os valores de BNP em pacientes com investigações cardíacas atendidos em um serviço de emergência e associá-los às evoluções dos mesmos, referentes a dados clínicos e procedimentos realizados. MÉTODOS: fizeram parte deste estudo 27 pacientes atendidos em um serviço de emergência e que tiveram alterações nas enzimas cardíacas creatinofosfoquinase (CK), creatinofosfoquinase fração MB (CK-MB) e Troponina. A dosagem de BNP foi realizada através da técnica de imunoensaio rápido por fluorescência. RESULTADOS: os valores alterados dos marcadores cardíacos são indicativos de injúria cardíaca, porém seus aumentos estão associados a eventos clínicos distintos. CONCLUSÃO: o valor médio do BNP foi maior naqueles pacientes submetidos à cirurgia cardiovascular, bem como seu aumento teve correlação com a ocorrência de óbitos.
Heart failure (HF) is a complex syndrome, which, despite medical advances related to the diagnosis and treatment of cardiovascular disease, is responsible for a high rate of mortality in the world. Factors such as lifestyle, difficulty of rapid diagnosis and aging population all contribute to the increased incidence and prevalence of such disease. A great ally for the laboratory diagnosis of early IC, though still little requested in clinical evaluations, is the B-type natriuretic peptide (BNP). OBJECTIVES: to determine the values of BNP in patients with cardiac investigations met in an emergency service and associate them to the same developments concerning clinical data and procedures. METHODS: this study took part in 27 patients in an emergency and who have had changes in cardiac enzymes creatine kinase (CK), creatine kinase MB fraction (CK-MB) and Troponin. The dosage of BNP was held through the technique of rapid immunoassay for fluorescence.RESULTS: the changed values of cardiac markers are indicative of cardiac injury, however their increases are associated with distinct clinical events. CONCLUSION: the average value of the BNP was higher in those patients undergoing cardiovascular surgery, as well as its increased had correlation with the occurrence of deaths.
Heart failure (HF) is a complex syndrome, which, despite medical advances related to the diagnosis and treatment of cardiovascular disease, is responsible for a high rate of mortality in the world. Factors such as lifestyle, difficulty of rapid diagnosis and aging population all contribute to the increased incidence and prevalence of such disease. A great ally for the laboratory diagnosis of early IC, though still little requested in clinical evaluations, is the B-type natriuretic peptide (BNP). OBJECTIVES: to determine the values of BNP in patients with cardiac investigations met in an emergency service and associate them to the same developments concerning clinical data and procedures. METHODS: this study took part in 27 patients in an emergency and who have had changes in cardiac enzymes creatine kinase (CK), creatine kinase MB fraction (CK-MB) and Troponin. The dosage of BNP was held through the technique of rapid immunoassay for fluorescence.RESULTS: the changed values of cardiac markers are indicative of cardiac injury, however their increases are associated with distinct clinical events. CONCLUSION: the average value of the BNP was higher in those patients undergoing cardiovascular surgery, as well as its increased had correlation with the occurrence of deaths.
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BNP; Insuficiência cardíaca
Citação
DIEHL, Marguele. Pesquisa da associação do BNP com a insuficiência cardíaca. 2015. Artigo (Graduação) – Curso de Biomedicina, Universidade do Vale do Taquari - Univates, Lajeado, 07 dez. 2015. Disponível em: http://hdl.handle.net/10737/1156.