Caracterização clínica dos pacientes com fendas orais em acompanhamento em um centro de referência para deformidades craniofaciais no Rio Grande do Sul entre os anos de 2010-2020
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2022-08
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Silva, André Anjos da
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Silva, Guilherme Liberato da
Contini, Verônica
Paskulin, Livia Dàvila
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Introdução: As fissuras labiopalatais são as malformações craniofaciais mais comuns e ocorrem quando há falha na fusão dos processos embrionários responsáveis pelo desenvolvimento da face. Sua etiologia é multifatorial, já que engloba tanto fatores ambientais quanto genéticos. O objetivo deste trabalho foi identificar o perfil epidemiológico dos pacientes com fendas orais em acompanhamento em um serviço multidisciplinar referência do Vale do Taquari, nos anos de 2010 a 2020. Além disso, também tem o propósito de conhecer as características clínicas dos pacientes com fissuras orais e avaliar os fatores associados às fendas orais no período da amostragem. Métodos: O presente trabalho é um estudo transversal qualiquantitativo, no qual foram analisados 1191 prontuários de pacientes que iniciaram atendimento no Serviço durante o período de 2010 a 2020. A partir dos dados coletados foi criado um banco de dados formatado no Excel, sendo realizada uma análise estática. Este trabalho foi aprovado pelo Comitê de Ética e Pesquisa (Coep/Univates). Resultados: Dos 1191 pacientes que foram elegíveis para esta pesquisa, o sexo masculino foi o mais acometido 56,9%. A fissura mais frequente foi transforame (44%). Em relação a lateralidade, houve um predomínio da fissura à esquerda (37,7%). O sexo masculino apresentou mais defeito pre-forame enquanto o femino mais pós forame. A mediana do fechamento do lábio se deu aos 6 meses e a do palato aos 18 meses. Quando houve malformações associadas, a sequência de Pierre Robin foi a mais relatada. Em relação ao histórico gestacional das mães dos pacientes atendidos, a maioria não fez uso de álcool, medicamentos, drogas e tabagismo. A maioria das mães também negou doenças maternas durante a gestação e histórico de aborto ou natimorto anterior. As mulheres com 20-30 anos foram as que apresentaram maior porcentagem de filhos com fendas orais. Conclusão: a partir do nosso estudo conseguimos afirmar que a fissura transforame é a mais prevalente, que o lado esquerdo é o mais acometido e que a fissura bilateral se mostrou relevante na amostra. Mesmo com muitos prontuários com falta de informações foi possível criar um banco de dados e traçar o perfil epidemiológico das fendas orais dos pacientes atendidos na instituição localizada no Vale do Taquari no Rio Grande do Sul.
Introduction: Cleft Lip and Palate are the most common craniofacial malformations and they occur when there is a failure in the fusion of the embryonic processes responsible for the development of the face. The etiology is multifactorial, as it encompasses both environmental and genetic factors. The objective of this study was to identify the epidemiological profile of patients with orofacial clefts that received a multidisciplinary service in the Taquari Valley from 2010 to 2020. In addition, it also aims to discover the clinical characteristics of patients with orofacial clefts and evaluate the factors associated with them in the sampling period. Method: This study is a qualitative and quantitative cross-sectional study, in which 1.191 medical records were analyzed of patients that started receiving care at the Service during the period of 2010 to 2020. From the data collected, a database was created in Microsoft Excel format and a statistical analysis was conducted. This study was approved by the Committee of Ethics and Research of Coep/Univates. Results: Of the 1,191 patients that were eligible for this study, the male sex was the most affected (56.9%). The most frequent cleft was Tranforamen (44%). Regarding laterality, there was a predominance of left- sided cleft (37.7%). The median of lip closure was at six months and of the palate at 18 months. When there were associated malformations, the Pierre Robin Sequence was the most reported. Regarding the gestational history of the mothers of the patients seen, most did not use alcohol, medication, drugs or smoke. Most mothers also denied maternal illnesses during pregnancy as well as previous history of miscarriage or stillbirth. Women aged 20 to 30 years had the highest percentage of children with orofacial clefts. Conclusion: From this study, it can be affirmed that the Transforamen Cleft is the most prevalent, that the left side is the most affected and that the bilateral cleft proved to be relevant in the sample. Even with many medical records lacking information, it was possible to create a database and trace the epidemiological profile of the oral clefts of patients treated at the institution located in Vale do Taquari in Rio Grande do Sul.
Introduction: Cleft Lip and Palate are the most common craniofacial malformations and they occur when there is a failure in the fusion of the embryonic processes responsible for the development of the face. The etiology is multifactorial, as it encompasses both environmental and genetic factors. The objective of this study was to identify the epidemiological profile of patients with orofacial clefts that received a multidisciplinary service in the Taquari Valley from 2010 to 2020. In addition, it also aims to discover the clinical characteristics of patients with orofacial clefts and evaluate the factors associated with them in the sampling period. Method: This study is a qualitative and quantitative cross-sectional study, in which 1.191 medical records were analyzed of patients that started receiving care at the Service during the period of 2010 to 2020. From the data collected, a database was created in Microsoft Excel format and a statistical analysis was conducted. This study was approved by the Committee of Ethics and Research of Coep/Univates. Results: Of the 1,191 patients that were eligible for this study, the male sex was the most affected (56.9%). The most frequent cleft was Tranforamen (44%). Regarding laterality, there was a predominance of left- sided cleft (37.7%). The median of lip closure was at six months and of the palate at 18 months. When there were associated malformations, the Pierre Robin Sequence was the most reported. Regarding the gestational history of the mothers of the patients seen, most did not use alcohol, medication, drugs or smoke. Most mothers also denied maternal illnesses during pregnancy as well as previous history of miscarriage or stillbirth. Women aged 20 to 30 years had the highest percentage of children with orofacial clefts. Conclusion: From this study, it can be affirmed that the Transforamen Cleft is the most prevalent, that the left side is the most affected and that the bilateral cleft proved to be relevant in the sample. Even with many medical records lacking information, it was possible to create a database and trace the epidemiological profile of the oral clefts of patients treated at the institution located in Vale do Taquari in Rio Grande do Sul.
Descrição
Palavras-chave
Fenda palatina; Fenda labiopalatal; Fenda labial; Fissura palatina; Cleft lip; Cleft palate; Cleft lip and palate; FUNDEF; Epidemiology; Características da população; Epidemiologia
Citação
BRUXEL, Carla Luísa. Caracterização clínica dos pacientes com fendas orais em acompanhamento em um centro de referência para deformidades craniofaciais no rio grande do sul entre os anos de 2010-2020. 2022. Dissertação (Mestrado) – Curso de Ciências Médicas, Universidade do Vale do Taquari - Univates, Lajeado, 05 ago. 2022. Disponível em: http://hdl.handle.net/10737/4880.